In this article, I’m going to teach you about the extraordinary benefits of using nootropics for opiate withdrawal and recovery. And I gotta tell ya…
I’ve been very excited about writing and publishing this piece.
The “nootropics” supplement category has become increasingly popular over the years.
College students, entrepreneurs, athletes, and other people commonly use nootropics to boost performance and enhance mental well-being.
The use of nootropics for opiate withdrawal and recovery is not yet mainstream knowledge, but my goal with this article is to help the world see just how beneficial these supplements are for opiate addiction recovery.
Table of Contents
- 1 1. Tianeptine Sulfate
- 2 2. Phenylpiracetam
- 3 3. Phenibut
- 4 4. Adrafinil
- 5 5. L-Theanine
- 6 6. Citicoline
- 7 7. More Racetams, Noopept, & Melatonin
- 8 8. Nootropic Stacks
- 9 9. Opiate Withdrawal Stack
- 10 10. Combining Nootropics with Kratom
Nootropics is an umbrella term for a class of chemicals — some naturally-occurring, some manmade — that give cognitive benefits to the human brain.
Also called smart drugs or cognitive enhancers, nootropics are drugs, supplements, or other substances that improve cognitive function in healthy individuals.
Nootropics primarily enhance executive cognitive functions such as:
As I stated earlier, nootropics have gained tremendous popularity recently with college students that need to study for an exam, entrepreneurs that want the “edge,” and even athletes seeking to enhance their performance.
After studying the science and research and using many different nootropics on myself, I’ve come to the wonderful realization that nootropics can be ABSOLUTELY PERFECT for opiate withdrawal and recovery.
The nootropics I’m going to focus on in this article were chosen due to their unique and beneficial mechanisms of action, which I not only studied but actually tested on myself.
And oh what fun it was!!!
Thus, without further ado, here are my Top 10 nootropics for opiate withdrawal and recovery.
1. Tianeptine Sulfate
Tianeptine sulfate is a powerful synthetic chemical compound that is used to treat major depressive disorder. For people struggling with anxiety or depression, it can have significant mood enhancing effects.
Tianeptine’s anxiolytic and mood-boosting effects, in addition to its neuroprotective and cognitive benefits, make it a popular nootropic.
Tianeptine (brand name Stablon) is a tricyclic medication used in some countries for depression, anxiety, and PTSD.
It’s unregulated in the US, making it legal to purchase online without a prescription.
Mechanisms of action: Selective Serotonin Reuptake Enhancer (SSRE), mu-opioid agonist, increases Brain-Derived Neurotrophic Factor (BDNF), increases dopamine.
At heavy doses above the therapeutic range, it is known to produce opioid effects such as sedation and stimulation, motivation enhancement, and euphoria.
How Tianeptine Made Me Feel
The Tianeptine Sulfate from Nootropics.com came in 25 mg capsules. I tried 25 mg, and an hour later, I felt some nice mood-brightening and relaxing effects. Then I took another 25 mg for a total of 50 mg and I FELT AMAZING!!!
I also wanted to test out the dosages above the therapeutic range, as I knew these higher dosages provided opioid agonist effects.
Well, it worked.
I used varying amounts from 100 mg to 800 mg.
It got me very, very, very high.
I was itching and nodding out, and I will never do that again.
Here is a video I made that goes into detail about the mechanisms of action of tianeptine, as well as my personal experiences using the nootropic.
How To Use Tianeptine Sulfate For Opiate Withdrawal
If you use tianeptine for opiate withdrawal or Post Acute Withdrawal Syndrome (PAWS), beware. This stuff can become crazy-addictive.
It makes you feel really good at low dosages, but the more you take, the better you feel as the opioid effects start to become stronger.
Many people have simply replaced one addiction with another by trying out tianeptine, so please, if you decide to use it, proceed with the utmost of caution, as you can become dependent on it and then develop withdrawal symptoms by trying to quit cold-turkey.
My Experiences using Tianeptine:
- 25 mg – Nice, happy, smooth mood-boost
- 50 mg – Nicer, happier mood-boost
- 400 mg – Felt like maybe 40-60 mg of hydrocodone…only better
- 800 mg – So high that I was seriously nodding out and getting itchy and irritated
- Acute Opiate Withdrawal – 100 mg to 400 mg, 3 times a day
- Post-Acute Withdrawal – 25 mg to 50 mg, 1-2 times a day
- Pain Relief – 25 mg to 100 mg, 1-2 times a day
- Depression – 25 mg, 1-2 times a day
- Anxiety – 25 mg, 1-2 times a day
Phenylpiracetam is a central nervous system stimulant and nootropic agent belonging to the racetam family of drugs. It is a modified version of piracetam, the original nootropic compound.
Racetams are a type of nootropic cognitive enhancing drug that all share a similar chemical structure.
Racetams are known for improving learning, memory, focus, mood and energy levels as well as positively affecting many of the basic components of brain health.
In studies, phenylpiracetam has shown the following effects:
- Improve memory, attention-switching, and problem-solving skills in patients with asthenia.
- Increase locomotor and antidepressant activity and improve memory in rats.
- Ability to suppress the anxiety and fear response in rats with induced immune stress.
- Reported to reduce the effects of sleep deprivation for the duration of its effects by many users.
How Phenylpiracetam Made Me Feel
Out of all the racetams I tried, phenylpiracetam was BY FAR my favorite. I LOVED IT!!! I took a 100 mg capsule of Phenylpiracetam from Nootropics.com, and within 30 minutes, I felt the effects come on.
I was driving my daughter to school when all of a sudden I felt this sense of motivation and also tranquility come over me.
It was a clean stimulant quality, without the accompanying anxiety that stimulants typically give me.
So I was feeling happy, motivated, relaxed, and on top of all that, the colors of the sky and trees were in High Definition.
Everything was more brilliant and beautiful, and MUSIC…oh my goodness, the music sounded much better than usual too, especially the second time I used phenylpiracetam, which was right before listening to binaural beats with headphones on.
How To Use Phenylpiracetam For Opiate Withdrawal
Phenylpiracetam was my favorite nootropic, and it wasn’t addictive like the tianeptine sulfate. Since it’s a dopamine reuptake inhibitor, it can be very useful during opiate withdrawal and PAWS.
When you get off opiates your dopamine goes “bye bye.”
So unless you want to feel depressed and totally exhausted with zero motivation, you’d better take something to help you increase dopamine.
I highly recommend using Phenylpiracetam from Nootropics.com for feelings of well-being after getting off opiates.
Capsules per day: 1 – 3
Effect onset: 30 – 60 minutes
Effect duration: Phenylpiracetam has a peak effect duration of 3-5 hours, with some residual benefits reported up to 10 hours later.
Extended use: Safe to use every other day (up to 3-4 times per week). After 2 weeks of use, taking 1 week off will avoid building tolerance.
Phenibut is a central nervous system (CNS) depressant that produces anxiolytic, disinhibiting, relaxing, and euphoric effects.
Phenibut is a closely related structural analog of the naturally occurring inhibitory neurotransmitter γ-aminobutyric acid (GABA). The addition of a phenyl ring allows it to cross the blood-brain barrier and produce psychoactive effects, a notable difference from GABA when taken exogenously.
Mechanisms of action: GABA-B receptor agonist (GABA-A at higher doses), binds to and blocks α2δ subunit-containing voltage-gated calcium channels (similarly to gabapentin and Lyrica), increases levels of dopamine.
While benzodiazepine drugs such as Xanax, Valium, Ativan, Klonopin, and Librium bind to the GABA-A receptors, phenibut binds to a different subtype – GABA-B – which drugs such as alcohol, baclofen, and GHB bind to.
Administering phenibut can lead to the following effects:
- Relief of Anxiety
- Feelings of Confidence and Clarity
- Mood Enhancement
- Feelings of Relaxation and Calmness
- Better Sleep
How Phenibut Made Me Feel
Before trying the Phenibut from Nootropics.com, I had tried a different brand and dosage of phenibut two years ago. I thought it was decent, but it certainly wasn’t anything I wanted to take again.
Thus, when I took my first 250 mg capsule of Phenibut from Nootropics.com, I was pleasantly surprised.
Within about 90 minutes, my mind became quiet and clear, and I was focused on the present moment with a deep feeling of full-body-mind relaxation.
The best way for me to describe the effects is to liken it to Valium or Klonopin, only without losing clarity and focus of mind, but instead, having an enhancement of cognition along with the anxiolytic effects.
How To Use Phenibut For Opiate Withdrawal
Phenibut can be highly addictive, and if you choose to use it, make sure you proceed with caution. I used to be addicted to Valium – and I gotta be honest – I could easily see myself getting addicted to phenibut if I didn’t have strict self-discipline.
Phenibut addiction is common, and if you become physiologically dependent on phenibut, make sure you taper off slowly, as a cold-turkey detox can lead to a horrific withdrawal syndrome.
Don’t combine phenibut with alcohol, opioids, benzodiazepines, or other gabaergics or CNS depressants, as this puts you at risk for overdose and even death.
Capsules per day: 1 – 6
Effect onset: 60 – 120 minutes
Effect duration: Phenibut is a medium-lasting social enhancer, with a peak effect duration of 5 hours. Calming can last 10 hours, with some residual benefits reported up to 20 hours later.
Extended use: Usage greater than 2-3 times per week will build tolerance and may lead to dependence. If effects subside, taking 1 week off can restore potency. If tolerance builds, exceeding standard doses will lead to dependence more quickly, so caution is recommended.
Adrafinil is a synthetic prodrug for modafinil, meaning supplementation of adrafinil leads to increased concentrations of modafinil in the body.
Modafinil is a wakefulness-promoting drug used for the treatment of disorders such as:
- Shift Work Sleep Disorder
- Excessive Daytime Sleepiness associated with Sleep Apnea
Modafinil is also used off-label to treat sedation and fatigue in many conditions, including:
- Chronic Fatigue Syndrome
- Opioid-Induced Sleepiness
Armed forces of several countries are known to have expressed interest in modafinil as an alternative to amphetamine—the drug traditionally employed in combat situations or lengthy missions where troops face sleep deprivation.
You cannot purchase modafinil as a nootropic here in the US because it’s currently classified as a Schedule IV controlled substance.
Luckily, you can purchase adrafinil and use it so your body will then use it as a precursor to creating modafinil.
How Adrafinil Made Me Feel
On a Friday morning, I took a 300 mg capsule of Adrafinil from Nootropics.com. I didn’t have anything planned for that day other than getting some work done on the computer.
Here is what happened…
Within an hour, the effects of adrafinil came on.
I was home alone for the day, and since I started to feel motivated and energized on the adrafinil, I decided to start a free 14-day trial of Click Funnels, which is a popular new software program for internet marketing.
For quite a while I’d been wanting to redesign the sales page for my online course Ultimate Opiate Detox 2.0, and I wanted to see if Click Funnels was better than the current software I had been using for years.
My brain was working so fast and efficient on the adrafinil, that I was actually able to design an awesome first-draft of my internet marketing sales page, without watching a single training video on how to use the software!!!
I felt like Bradley Cooper’s character in the movie Limitless.
In Limitless, the main character is introduced to a nootropic drug called NZT-48, which gives him the ability to fully utilize his brain and vastly improve his lifestyle.
After taking adrafinil, it was as if I had been using Click Funnels to design internet marketing sales pages for years.
I couldn’t believe it.
Mechanisms of action: Adrafinil is a precursor to modafinil. Modafinil is a dopamine reuptake inhibitor, among other things. At the time I am writing this, the therapeutic mechanism of action of modafinil for narcolepsy and sleep-wake disorders remains unknown.
How To Use Adrafinil For Opiate Withdrawal
At this point, I really need to express how excited and grateful I am that someone on my blog asked me if I knew anything about using adrafinil for the fatigue caused by coming off opiates.
Once I studied the science, I knew it had great potential, but it was only after I tested adrafinil out on myself that I realized it was the perfect nootropic to use for reducing fatigue while getting off opiates.
Adrafinil is a game-changer in this regard.
I had found plenty of opiate withdrawal remedies that could eliminate all of the other withdrawal symptoms (anxiety, insomnia, restless legs, depression, diarrhea, etc.).
But for years I didn’t find anything that could help you get your energy back FAST. Now I have something for fatigue that works in an hour or less…thank you adrafinil!!!
Capsules per day: 1 – 2
Effect onset: 45 – 60 minutes
Effect duration: Adrafinil is a long-lasting cognitive enhancer, with a peak effect duration of 8 hours. Improved cognition can last 24 hours, with some residual benefits reported up to 60 hours later.
Extended use: Most effective when taken every other day (up to 3-4 times per week). After 2 weeks of use, taking 1 week off will avoid building tolerance.
- One 300 mg capsule of Adrafinil is equivalent to 100 mg of Modafinil.
- Keeping hydrated on Adrafinil is particularly important, as dehydration can lead to headaches.
- Usage in the morning is optimal for avoiding sleep disruption due to increased wakefulness.
- Adrafinil is sometimes supplemented with L-Theanine, Phenibut or Citicoline to amplify the cognitive effects, and reduce residual anxiety or stress.
L-theanine is a nondietary amino acid found primarily in plant and fungal species. It was discovered as a constituent of green tea (Camellia sinensis) in 1949, and in 1950, a laboratory in Japan successfully isolated it from gyokuro leaf (a type of green tea) which has a high l-theanine content.
Along with green tea, l-theanine is also found in black tea, white tea, and certain types of mushrooms.
L-theanine has been shown to have the following benefits:
- Reduce Mental and Physical Stress
- Improve Cognition
- Boost Mood
- Reduce Opiate Withdrawal Symptoms
Mechanisms of action: Increases serotonin, dopamine, and GABA. It is able to cross the blood-brain barrier and produce psychoactive effects.
L-Theanine significantly increases alpha wave production in the brain. Alpha brain waves are most present in a wakeful state that is characterized by a relaxed and effortless alertness. Alpha states have been described variously as sublime, flying, floating, lightness, peace, and tranquility.
Alpha waves are present when your brain is in an idling default-state typically created when you’re daydreaming or consciously practicing mindfulness or meditation.
Along with being abundant in these plant sources, l-theanine is also available as a nootropic supplement.
How L-Theanine Made Me Feel
I drink green tea daily, so I’m no stranger to the pleasant effects of l-theanine. However, when I tried L-Theanine from Nootropics.com, this was the first time I’ve used the isolated nootropic supplement.
The benefit of this is simply being able to use a much higher dosage of l-theanine.
All I can say is WOW!!!
It made me totally relaxed, happy, and my mind remained clear in the present moment. Typically I think a lot of thoughts throughout the day, as my mind is very active.
But on the l-theanine, I was more centered, and my mind was calmer. In fact, my mind was as still as the water in a lake on a windless day.
How To Use L-Theanine For Opiate Withdrawal
I highly recommend taking l-theanine for opiate withdrawal, and my favorite Opiate Withdrawal Supplement goes well with this and other nootropics too.
Capsules per day: 1 – 6
Effects onset: 30 – 60 minutes
Effects duration: Main effect lasts 2 – 4 hours, with some residual effects up to 10 hours.
Extended use: Some diminished effect after 7 days of continual use. A break of 4 – 7 days can stave off tolerance.
Citicoline is a nutrient actually found in the body in addition to being a nutritional supplement. It is a water-soluble compound that is an essential intermediary in the synthesis of phosphatidylcholine, which is a major component of grey matter brain tissue.
Your brain makes up only 2% of your body weight, yet it consumes roughly 20% of your body’s energy when at rest. That means the human brain needs a whole lot of nutrition to stay alert and focused throughout the day.
Citicoline is nature’s way of keeping the brain’s energy-producing centers firing.
Taking citicoline can lead to the following benefits:
- Enhanced Cognition
How Citicoline Made Me Feel
When paired with cognition-enhancing nootropics such as adrafinil, phenylpiracetam, and noopept, citicoline amplifies the brain-boosting effects, whilst reducing the risks of headaches.
I tried Citicoline with the other nootropics, after first using the nootropics without Citicoline.
I DEFINITELY felt even better effects from all the nootropics when I stacked them with Citicoline, and I highly recommend that you try this out as well.
How To Use Citicoline For Opiate Withdrawal
Capsules per day: 1 – 4
Effects onset: 30 – 60 minutes
Effect duration: Main effect lasts 6-8 hours, with some residual effects up to 12 hours.
Extended use: As side effects may be compounded with extended use, taking a week off can restore potency and allow for neural regulation.
- Usage in the morning is optimal for avoiding sleep disruption due to increased wakefulness.
- An excess of choline may amplify existing anxieties or deepen depressive episodes. Citicoline is therefore not advised for individuals with a history of these conditions.
7. More Racetams, Noopept, & Melatonin
So far, I’ve provided detailed information on my six favorite nootropics for opiate withdrawal and recovery. For the remaining four nootropics I tried from Nootropics.com, I’m going to lump them all in right here.
Honestly, I didn’t love them quite as much as their nootropic brothers and sisters.
Don’t get me wrong…I liked them, but compared to the other six nootropics I tried, I simply didn’t want to spend a lot of time writing about them in this already-long article.
Thus, here is just a brief overview on these nootropics:
- Piracetam – The classic, original nootropic, which boots cognition, motivation, etc.
- Aniracetam – Similar to Piracetam, but also helps with anxiety in addition to those effects.
- Noopept – Boosts cognition, motivation, and productivity, and promotes the generation of new neurons.
- Melatonin – Helps to regulate your sleep cycle and thus can be helpful for insomnia.
8. Nootropic Stacks
While I thoroughly enjoyed trying out the individual nootropics, I felt the absolute BEST when I used different “nootropic stacks.”
A nootropic stack, simply put, is the combination of two or more nootropics that have beneficial effects on memory, learning, focus, or motivation, in order to create a synergistic effect in the brain greater than any increase in cognition than the nootropics you “stack” could create on their own.
Up until my experimenting, I had never tried a nootropic stack.
How did the experimenting go?
Well, let’s just say that I will certainly be making nootropic stacking a regular part of my life from here on out!!!
Here are the stacks that I loved the most:
9. Opiate Withdrawal Stack
While all of the nootropic stacks I just mentioned could be very helpful for opiate withdrawal, none of them are customized for that job.
Thus, I thought it would be fun and helpful to create my own Opiate Withdrawal Stack of nootropics.
So that’s exactly what I did.
Here is my Opiate Withdrawal Stack:
Please Note: Along with this nootropic stack, I would also take loperamide HCL. All of these together would help a person to feel okay while coming off opiates. I realize this is expensive, and so a leaner version of this that would still be quite effective would be: Phenibut, L-Theanine, Adrafinil, and of course the loperamide as well.
*Also, due to its enormous popularity, Tianeptine Sulfate is out of stock quite a bit. In this case, don’t worry one bit. Simply replace Tianeptine Sulfate with kratom. Which leads us nicely into the next section…
10. Combining Nootropics with Kratom
Probably the most fun I’ve had in years was the part of my experiment where I decided it would be interesting to use nootropics with kratom.
The effects were truly sensational.
The absolute best I felt was when I administered the following, which I named the Ultimate Euphoria Stack.
Ultimate Euphoria Stack:
Kratom and certain nootropics can be addictive and dangerous. It is a dual-edged sword. On one side, it can help you reduce your opiate withdrawal symptoms to almost nothing or even nothing.
On the other side, there is a potential to get addicted to these substances, and the battle of addiction continues, albeit with new addictive substances.
I’m really stoked we have nootropics and kratom available online because it gives us some power back.
I like to do my own research and try things out on myself if I think they would help me. It’s much preferable to having to go to the doctor and being at their mercy to get the help I need in the form I need it in.
Don’t get me wrong, I think doctors are a great resource, and helpful for many things. I also like to have more options, and thus I really appreciate having all of these amazing nootropics and kratom available online without a prescription.
I hope you enjoyed reading this article because I really loved writing it for you. To learn more tips to get off opiates, click here now to view my best home detox program.
And if you’re ready to do some online shopping for these life-enhancing nootropics…
If you have any comments or questions on the use of nootropics for opiate withdrawal, please post them in the comment box below.