More and more people are starting to learn about the benefits of gabapentin for opiate withdrawal symptoms. Gabapentin (brand name Neurontin) is a gamma-aminobutyric acid (GABA) analogue that was originally developed for the treatment of epilepsy, pain relief and neuropathic pain.
Gabapentin was initially synthesized to mimic the chemical structure of the neurotransmitter GABA. Gabapentin is effective in the treatment of social anxiety disorder, panic disorder, and generalized anxiety disorder. Results with human and rat brain Nuclear magnetic resonance (NMR) spectroscopy indicate that gabapentin increases GABA synthesis, probably by modulating, as it does in-vitro, the action of the GABA synthetic enzyme, glutamic acid decarboxylase and the glutamate synthesizing enzyme, branched-chain amino acid transaminase.
Gabapentin is now one of the most common medications used on people with alcohol, crack, opiate and other addictions. The purpose of this article is to show you how gabapentin reduces the severity of withdrawal symptoms experienced by those physically dependent on opioid analgesics such as heroin, morphine, and Methadone. I will do this by explaining the abstract and results from two important studies on gabapentin for opiate withdrawal.
Gabapentin for Opiate Withdrawal Symptoms Study #1
The first study I will refer to on gabapentin for opiate withdrawal symptoms was done in Iran. There is an extremely potent drug in Iran called “Iranian crack” that many individuals have become addicted to. Iranian crack is mostly composed of condensed heroin. Although multiple medications have been studied for the treatment of dependence to various substances, no medications had previously been shown to have a robust effect on Iranian crack craving and its-related side effects.
This randomized double-blind clinical trial examined the effectiveness of gabapentin for opiate withdrawal symptoms in patients undergoing inpatient treatment for Iranian crack, which contains primarily condensed heroin.
60 men ages 18 to 60 years old with an addiction to Iranian crack were put into two groups: gabapentin group and placebo group. During the double-blind phase, study medication was titrated to thirty capsules of either gabapentin or placebo orally 45 min prior to bedtime over a duration of one week. Each capsule received by the medication group contained 300 mg of gabapentin (one capsule) for the first day and then 300 mg/q12h for the second day, 300 mg/q8h for the third day, and 600 mg/q8h for the other days. Each subject received one capsule at bedtime for three nights, then two capsules at bedtime for four nights. After one week passed, the Subjective Opioid Withdrawal Scale (SOWS) was measured by a physician.
Results: Pain severity during the most of detoxification duration was significantly lower in the gabapentin group compared with the placebo group. It is suggested that gabapentin may have an effective role in removing heroin withdrawal-related pain.
Gabapentin for Opiate Withdrawal Symptoms Study #2
The second study done with gabapentin for opiate withdrawal symptoms consisted of 27 patients that were addicted to opiates. In the study, patients were put on methadone for a rapid three week detoxification. They were then divided into two groups. The first group was given 900 mg of gabapentin for opiate withdrawal symptoms per day. The 2nd group was given 1600 mg of gabapentin for opiate withdrawal symptoms per day.
Results: Gabapentin with a dose of 1600 mg/d was significantly superior to a dose of 900 mg/d in decreasing severity of coldness, diarrhea, dysphoria, yawing, and muscle tension.
Gabapentin for Opiate Withdrawal Symptoms Dosage
Based on the findings from both studies, it appears as though one could use the same amount of gabapentin to achieve similar results. Unfortunately, gabapentin for opiate withdrawal symptoms is only available by prescription from a doctor. However, I did some research and found a powerful natural supplement available online without a prescription that can be used as a gabapentin for opiate withdrawal symptoms alternative.
Gabapentin for Opiate Withdrawal Symptoms Alternative
Recently I stumbled across some articles on a supplement called phenibut that piqued my interest. Since gabapentin was originally synthesized to mimic the neurotransmitter GABA, I wanted to find a strong natural alternative that was similar to this that was available without a prescription. Phenibut is a derivative of the natural neurotransmitter GABA, which has inhibitory qualities that can produce tranquilizing and anxiolytic (anxiety reducing) effects.
About a week ago I tried phenibut for the first time. I did this from a strictly investigative perspective to make sure that it worked on me before I felt comfortable recommending it for opiate withdrawal symptoms. I took a 500 mg dose, and within a few hours I was feeling very relaxed. A few days later I took 1000 mg and noticed complete muscle relaxation, easing of tension, and I had a very deep sleep that night as well. It was by far the strongest natural remedy for anxiety reduction I’ve ever used. In fact, it was too strong for me, but it is the perfect strength for opiate withdrawal anxiety and insomnia.
If you aren’t able to obtain a prescription of gabapentin from your doctor, phenibut can be used to receive the following benefits during opiate withdrawal:
- Calming of the nervous system
- Mood booster
- Eases anxiety and promotes total relaxation
- Powerful sleep aid
Click here now to view my best home detox program. If you have any questions on phenibut or gabapentin for opiate withdrawal symptoms, please don’t hesitate to leave it in the comment box below.